Integrin alpha 5 (ITGA5) Rabbit Polyclonal Antibody
| Product Data | |
| Application | FC, IF, IHC, IP, WB |
|---|---|
| Recommended Dilution | WB: 1/1000-1/2000 IHC: 1/50-1/200 ICC/IF: 1/50-1/200 IP: 1/50 FC: 1/50 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | A synthesized peptide derived from human Integrin alpha 5 |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | Affinity Chromatography |
| Conjugation | Unconjugated |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Predicted Protein Size | 150kDa |
| Gene Name | integrin subunit alpha 5 |
| Database Link | |
| Background | Swiss-Prot Acc.P08648.Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1. ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1. |
| Synonyms | CD49e; FNRA; VLA-5; VLA5A |
| Reference Data | |
Write Your Own Review
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.