HAT1 Rabbit Monoclonal Antibody [Clone ID: R02-4J1]
| Product Data | |
| Clone Name | R02-4J1 |
|---|---|
| Application | IF, IHC, IP, WB |
| Recommended Dilution | WB: 1/1000 IHC: 1/100 ICC/IF: 1/100 IP: 1/20 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | Recombinant protein of human KAT1 |
| Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Concentration | lot specific |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Predicted Protein Size | Calculated MW: 50 kDa; Observed MW: 45 kDa |
| Gene Name | histone acetyltransferase 1 |
| Database Link | |
| Background | Swiss-Prot Acc.O14929.Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage. |
| Synonyms | KAT1 |
| Reference Data | |
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