Geminin (GMNN) Rabbit Polyclonal Antibody
Product Data | |
Application | IF, IHC, WB |
---|---|
Recommended Dilution | WB: 1/500-1/1000 IHC: 1/50-1/200 ICC/IF: 1/50-1/200 |
Reactivity | Human |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | A synthesized peptide derived from human Geminin |
Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Concentration | lot specific |
Purification | Affinity Chromatography |
Conjugation | Unconjugated |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Stability | 1 year |
Shipping | Blue Ice |
Predicted Protein Size | 30kDa |
Gene Name | geminin, DNA replication inhibitor |
Database Link | |
Background | Swiss-Prot Acc.O75496.Inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle. |
Synonyms | Gem; geminin; RP3-369A17.3 |
Reference Data |
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