DOHH Rabbit Monoclonal Antibody [Clone ID: R04-4I8]
Specifications
| Product Data | |
| Clone Name | R04-4I8 |
|---|---|
| Application | IP, WB |
| Recommended Dilution | WB: 1/1000 IP: 1/20 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthetic peptide of human DOHH |
| Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Concentration | lot specific |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Predicted Protein Size | Calculated MW: 33 kDa; Observed MW: 33 kDa |
| Gene Name | deoxyhypusine hydroxylase/monooxygenase |
| Database Link | |
| Background | Swiss-Prot Acc.Q9BU89.Catalyzes the hydroxylation of the N6-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine (PubMed:16533814, PubMed:16371467, PubMed:19706422). Hypusination is unique to mature eIF-5A factor and is essential for its function . |
| Synonyms | hDOHH; HLRC1; MGC4293 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
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