Chk2 (CHEK2) Rabbit Polyclonal Antibody
| Product Data | |
| Application | IF, IHC, IP, WB |
|---|---|
| Recommended Dilution | WB: 1/10000-1/20000 IHC: 1/50-1/200 ICC/IF: 1/50-1/200 IP: 1/50 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | A synthesized peptide derived from human Chk2 |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | Affinity Chromatography |
| Conjugation | Unconjugated |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Predicted Protein Size | 62kDa |
| Gene Name | checkpoint kinase 2 |
| Database Link | |
| Background | Swiss-Prot Acc.O96017.These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function. |
| Synonyms | bA444G7; CDS1; CHK2; HuCds1; LFS2; OTTHUMP00000199044; OTTHUMP00000199045; OTTHUMP00000199116; PP1425; RAD53 |
| Reference Data | |
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