ATP6V0D1 Rabbit Monoclonal Antibody [Clone ID: R07-1A5]
| Product Data | |
| Clone Name | R07-1A5 |
|---|---|
| Application | IF, IHC, IP, WB |
| Recommended Dilution | WB: 1/1000 IHC: 1/20 ICC/IF: 1/50 IP: 1/20 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | Recombinant protein of human ATP6V0D1 |
| Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Concentration | lot specific |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Predicted Protein Size | Calculated MW: 40 kDa; Observed MW: 40 kDa |
| Gene Name | ATPase H+ transporting V0 subunit d1 |
| Database Link | |
| Background | Swiss-Prot Acc.P61421.Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis . May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium . In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633). |
| Synonyms | ATP6D; ATP6DV; P39; VATX; Vma6; VPATPD |
| Reference Data | |
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