Alpha Dystroglycan (DAG1) Rabbit Polyclonal Antibody
| Product Data | |
| Application | ELISA, ICC/IF, IP, WB |
|---|---|
| Recommended Dilution | WB,1:1000 - 1:5000 IF/ICC,1:20 - 1:100 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
| Reactivity | Human, Mouse, Rat |
| Modification | Unmodified |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Buffer | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| Concentration | lot specific |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 97kDa |
| Gene Name | dystroglycan 1 |
| Database Link | |
| Background | This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein. |
| Synonyms | 156DAG; A3a; AGRNR; alpha-dystroglycan; beta-dystroglycan; DAG |
| Reference Data | |
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