Activin A Receptor Type IC (ACVR1C) Rabbit Polyclonal Antibody
Product Data | |
Application | ELISA, IHC, WB |
---|---|
Recommended Dilution | WB,1:500 - 1:1000 IHC-P,1:100 - 1:200 ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
Reactivity | Human, Mouse, Rat |
Modification | Unmodified |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Buffer | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20℃. Avoid freeze / thaw cycles. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Predicted Protein Size | 55kDa |
Gene Name | activin A receptor type 1C |
Database Link | |
Background | ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]). |
Synonyms | ACTR-IC; ACVRLK7; ALK-7; ALK7 |
Reference Data |
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