ZFYVE19 Rabbit Polyclonal Antibody
Product Data | |
Application | IHC, WB |
---|---|
Recommended Dilution | WB: 500-2000 WB positive control: Hela and A431 cells IHC: 50-200 Positive control: Human tonsil Predicted cell location: Cytoplasm |
Reactivity | Human |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human ZFYVE19 |
Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C. |
Stability | 1 year |
Shipping | Blue Ice |
Predicted Protein Size | 52 kDa |
Gene Name | zinc finger FYVE-type containing 19 |
Database Link | |
Background | ZFYVE19 (zinc finger, FYVE domain containing 19), also known as MPFYVE (MLL partner containing FYVE domain), is a 471 amino acid protein that contains one FYVE-type zinc finger. Expressed in heart, brain, kidney, skeletal muscle and liver, ZFYVE19 may participate in transcriptional regulation events within the cell. Defects in the gene encoding ZFYVE19 are associated with acute myeloblastic leukemia (AML), a rapidly progressing cancer of the myeloid line of white blood cells that is characterized by fever, anemia, bone pain, shortness of breath and frequent infections. Three isoforms of ZFYVE19 exist due to alternative splicing events. |
Synonyms | FLJ14840; MPFYVE |
Reference Data |
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