BOB1 (POU2AF1) Mouse Monoclonal Antibody [Clone ID: TG14]

SKU
TA355222
B Cell Specific Octamer Binding Protein-1 (BOB-1) Mouse Monoclonal Antibody
$1,140.00
3 Weeks*
Specifications
Product Data
Clone Name TG14
Application IHC
Recommended Dilution 1:20
Reactivity Human
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen A prokaryotic recombinant protein corresponding to 116 amino acids of the C-terminal region of the
Specificity Human B cell specific octamer binding protein-1 (BOB-1).
Buffer Liquid tissue culture supernatant containing 15 mM sodium azide as a preservative
Conjugation Unconjugated
Storage Store at 2-8°C
Stability 12 months
Shipping Blue Ice
Gene Name POU class 2 associating factor 1
Database Link
Background B cell specific octamer binding protein-1 (BOB-1), also known as OBF-1 and OCA-B, is a lymphocyte specific transcriptional coactivator protein. It interacts with OCT1 and OCT2 transcription factors and contributes to the transcriptional activity of octamer motifs. BOB-1 is used alongside OCT2 to differentiate between classic Hodgkin's lymphoma (both down regulated) and nodular lymphocyte predominant Hodgkin's lymphoma.
BOB-1 has been reported to be detectable in all B cell populations found in reactive lymphoid tissues. The strongest expression being found in germinal center B cells and plasma cells.
The expression of BOB-1 in B cell tumors has been reported to be variable. Used alongside OCT2 to differentiate between classic Hodgkin's lymphoma (both down regulated) and nodular lymphocyte predominant Hodgkin's lymphoma.
Synonyms BOB-1; BOB1; OBF-1; OBF1; OCA-B; OCAB
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.