SARS-CoV-2 N Protein Rabbit Monoclonal Antibody [Clone ID: DM23]

SKU TA355172

SARS-CoV-2 Nucleocapsid rabbit monoclonal antibody, clone DM23

Product Data

• Clone Name: DM23
• Application: ELISA
• Recommended Dilution: ELISA 1/5000-1/10000
• Reactivity: SARS-CoV-2
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Recombinant SARS-CoV-2 Nucleocapsid (Met1-Ala419) ([TP723996]) produced by using E. coli
• Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.; Preservative: 0.1% Procline 300
• Reconstitution Method: Reconstitute with deionized water
• Purification: Purified from cell culture supernatant by affinity chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C for 12 months (Avoid repeated freezing and thawing)
• Stability: 12 months from date of despatch
• Shipping: Ambient
• Predicted Protein Size: 45kDa
• Background: Coronavirus contain most of nucleocapsid protein. Coronavirus nucleoproteins (N proteins) localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. The nucleolus is the site of ribosome biogenesis and sequesters cell cycle regulatory complexes. Two of the major components of the nucleolus are fibrillarin and nucleolin. These proteins are involved in nucleolar assembly and ribosome biogenesis and act as chaperones for the import of proteins into the nucleolus. Regarding of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is a tool for diagnostic.

Reference Data