CD51 (ITGAV) Rat Monoclonal Antibody [Clone ID: Avß6 62ow.17]

CAT#: TA352873L

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Rat monoclonal Anti-Integrin aVβ6 Clone Avβ6 62ow.17

Product Datasheet for 'TA352873L'

USD 1,140.00

2 Weeks

    • 500 ug

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Product Data
Clone Name Avβ6 62ow.17
Recommend Dilution IHC ; WB
Reactivity Human
Host Rat
Isotype IgG1
Clonality Monoclonal
Immunogen Mouse fibroblasts retrovirally infected with cDNA to human beta6 (3T3β6.19). Cells expressed a mouse/human avβ6 chimera.
Formulation PBS with 0.02% Sodium Azide
Concentration 1 mg/ml
Purification Purified by affinity chromatography.
Gene Name integrin subunit alpha V
Background Alpha-v beta-6 is upregulated on cancers and during tissue remodelling but is weak absent on resting adult tissues. It promotes invasion and correlates with poor survival. It is likely to be good therapeutic target.
Synonyms CD51; MSK8; VNRA; VTNR
Note Does not recognise mouse avβ6
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cell adhesion molecules (CAMs), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer
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68 Mouse Clones