SCP1 (SYCP1) Rabbit Polyclonal Antibody
Product Data | |
Application | IHC |
---|---|
Recommended Dilution | IHC: 25-100 Positive control: Human colon cancer Predicted cell location: Nucleus |
Reactivity | Human |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human SYCP1 |
Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Gene Name | synaptonemal complex protein 1 |
Database Link | |
Background | The synaptonemal complex protein 1 (SCP-1), also known as SYCP1(A), SYN1(I) and HOM-TES-14, is a protein product of human chromosome 1p13-p12. SCP-1 is a major component of the transverse filaments of synaptonemal complexes and functions by pairing homologous chromosomes during meiotic prophase in spermatocytes, which is an essential step for the generation of haploid cells in meiosis I. SCP-1 is expressed in the testis, adult brain, some malignant gliomas, breast, renal cell and ovarian cancer. SCP-1 is known to be selectively expressed during the meiotic prophase of spermatocytes and shows cell cycle phase-independent nuclear expression in cancer cells. |
Synonyms | CT8; HOM-TES-14; SCP-1; SCP1 |
Reference Data |
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