BAFF Receptor (TNFRSF13C) Rabbit Polyclonal Antibody

SKU TA351445

Rabbit Polyclonal Anti-TNFRSF13C Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 200-1000; WB positive control: Mouse thymus tissue; IHC: 50-200; Positive control: Human thyroid cancer; Predicted cell location: Cytoplasm
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human TNFRSF13C
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 19 kDa
• Gene Name: tumor necrosis factor receptor superfamily member 13C
• Database Link:
  NP_443177
  Q96RJ3
• Background: B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
• Synonyms: BAFF-R; BAFFR; BROMIX; CD268; CVID4; prolixin

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Primary immunodeficiency