MCHR (MCHR1) Rabbit Polyclonal Antibody

CAT#: TA351389

Rabbit Polyclonal Anti-MCHR1 Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-6: Human fetal liver tissue Human testis tissue 293T cells A172 cells mouse brain tissue human fetal brain tissue Primary antibody: TA351389 (MCHR1 Antibody) at dilution 1/350 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA351389 (MCHR1 Antibody) at dilution 1/30 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA351389 (MCHR1 Antibody) at dilution 1/30, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA351389 (MCHR1 Antibody) at dilution 1/30 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA351389 (MCHR1 Antibody) at dilution 1/30, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human fetal liver and testis tissue, 293T and A172 cells, mouse brain and human fetal brain tissue
  IHC: 50-200
  Positive control: Human ovarian cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human MCHR1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 46 kDa
• Gene Name: melanin concentrating hormone receptor 1
• Database Link:
  NP_005288
  Entrez Gene 83567 RatEntrez Gene 207911 MouseEntrez Gene 2847 Human
  UniProt ID Q99705
• Background: MCHR1, a member of the G protein coupled receptor family 1, is an integral plasma membrane protein which binds melanin concentrating hormone. MCHR1 can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, MCHR1 does not seem to bind somatostatin.
• Synonyms: GPR24; MCH-1R; MCH1R; SLC-1; SLC1

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction