Cullin 4B (CUL4B) Rabbit Polyclonal Antibody

SKU TA351115

Rabbit Polyclonal Anti-CUL4B Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 50-200; Positive control: Human thyroid cancer; Predicted cell location: Nucleus
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human CUL4B
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: cullin 4B
• Database Link:
  NP_003579
  Q13620
• Background: This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: CUL-4B; MRXHF2; MRXS15; MRXSC; SFM2

Reference Data

• Protein Pathways: Nucleotide excision repair, Ubiquitin mediated proteolysis