Collagen VII (COL7A1) Rabbit Polyclonal Antibody

SKU TA351108

Rabbit Polyclonal Anti-COL7A1 Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 500-2000; WB positive control: Hela cell lysate; IHC: 50-100; Positive control: Human liver cancer; Predicted cell location: secreted
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human COL7A1
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: collagen type VII alpha 1
• Database Link:
  NP_000085
  Q02388
• Background: This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen.
• Synonyms: EBD1; EBDCT; EBR1; NDNC8

Reference Data

• Protein Families: Druggable Genome