Bile salt activated lipase (CEL) Rabbit Polyclonal Antibody

SKU TA351006

Rabbit Polyclonal Anti-CEL Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 500-2000; WB positive control: Mouse Pancreas tissue lysate; IHC: 50-200; Positive control: Human gastric cancer; Predicted cell location: secreted
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human CEL
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 79 kDa
• Gene Name: carboxyl ester lipase
• Database Link:
  NP_001798
• Background: The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted.
• Synonyms: BAL; BSDL; BSSL; CEase; CELL; FAP; FAPP; LIPA; MODY8

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Glycerolipid metabolism, Metabolic pathways, Steroid biosynthesis