l Afadin (AFDN) Rabbit Polyclonal Antibody

SKU TA350791

Rabbit Polyclonal Anti-MLLT4 Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 50-200; Positive control: Human colon cancer; Predicted cell location: Cytoplasm
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human MLLT4
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4
• Database Link:
  NP_005927
  P55196
• Background: This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6;11)(q27;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.
• Synonyms: AF-6; AF6; AFADIN; FLJ34371; RP3-431P23.3

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Adherens junction, Leukocyte transendothelial migration, Tight junction