TRPC4AP Rabbit Polyclonal Antibody

SKU TA350547

Rabbit Polyclonal Anti-TRPC4AP Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 30-150; Positive control: Human thyroid cancer; Predicted cell location: Cytoplasm and Cell membrane
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human TRPC4AP
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: transient receptor potential cation channel subfamily C member 4 associated protein
• Database Link:
  NP_056453
  Q8TEL6
• Background: TRPC4AP (transient receptor potential cation channel, subfamily C, member 4 associated protein), also known as TRUSS or TRRP4AP, is a 797 amino acid protein that is expressed in a variety of tissues, with highest expression in liver, heart, testis and brain. Thought to function as a scaffolding protein, TRPC4AP interacts with TNF-R1 and may both link TNF-R1 to the IKK signalsome complex, and participate in the activation of NFκB p50, an event that occurs in response to TNF-R1 ligation. TRPC4AP exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome.
• Synonyms: C20orf188; PPP1R158; TRRP4AP; TRUSS

Reference Data

• Protein Families: Druggable Genome