GRIM19 (NDUFA13) Rabbit Polyclonal Antibody
Product Data | |
Application | IHC, WB |
---|---|
Recommended Dilution | WB: 500-2000 WB positive control: Mouse skeletal muscle and human hepatocellsular carcinoma tissue IHC: 100-300 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein of human NDUFA13 |
Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 17 kDa |
Gene Name | NADH:ubiquinone oxidoreductase subunit A13 |
Database Link | |
Background | This gene encodes a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. The protein is required for complex I assembly and electron transfer activity. The protein binds the signal transducers and activators of transcription 3 (STAT3) transcription factor, and can function as a tumor suppressor. The human protein purified from mitochondria migrates at approximately 16 kDa. Transcripts originating from an upstream promoter and capable of expressing a protein with a longer N-terminus have been found, but their biological validity has not been determined. |
Synonyms | B16.6; CDA016; CGI-39; GRIM-19; GRIM19 |
Reference Data | |
Protein Families | Transcription Factors, Transmembrane |
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