APPBP1 (NAE1) Rabbit Polyclonal Antibody

SKU TA349491

Rabbit Polyclonal Anti-NAE1 Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 15-50; Positive control: Human cervical cancer; Predicted cell location: Nucleus
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human NAE1
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: NEDD8 activating enzyme E1 subunit 1
• Database Link:
  NP_003896
  Q13564
• Background: The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
• Synonyms: A-116A10.1; APPBP1; HPP1; ula-1

Reference Data

• Protein Pathways: Alzheimer's disease