NOSTRIN Rabbit Polyclonal Antibody

SKU TA349121

Rabbit Polyclonal Anti-NOSTRIN Antibody

Product Data

• Application: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: NOSTRIN antibody was raised against a 17 amino acid peptide near the carboxy terminus of human NOSTRIN.
• Buffer: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: NOSTRIN antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: Predicted: 47, 53, 56, 62 kDa; Observed: 68 kDa
• Gene Name: nitric oxide synthase trafficking
• Database Link:
  NP_443178
  Q8IVI9
• Background: NOSTRIN. also known as endothelial nitric oxide synthase traffic inducer, is a member of the Pombe Cdc15 homology (PCH) family of proteins which may function as the modulator of the subcellular localisation and activity of endothelial nitric oxide synthase (eNOS) (1,2). It decreases NOS3 activity by inducing its translocation away from the plasma membrane (3). NOSTRIN typically exists as a trimer and is expressed in the vascular endothelial cells of highly vascularized tissues such as placenta, lung, kidney and heart. NOSTRIN is necessary for proper vascular development in zebrafish and postnatal retinal angiogenesis in mice (4,5).
• Synonyms: APG4A; AUTL2

Reference Data