HDAC6 Rabbit Polyclonal Antibody

SKU TA349074

Rabbit Polyclonal Anti-HDAC6 Antibody

Product Data

• Application: IF, IHC, WB
• Recommended Dilution: WB: 0.5 - 1 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: HDAC6 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human HDAC6
• Buffer: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: HDAC6 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: Predicted: 134 kDa; Observed: 145 kDa
• Gene Name: histone deacetylase 6
• Database Link:
  NP_006035
  Q9UBN7
• Background: The histone deacetylase (HDAC) family contains multiple members which are divided into four classes. Class II of the HDAC family comprises six members, HDAC4, 5, 6, 7, 9 and 10, each of which appear to have tissue-specific roles (1). HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other (2). HDAC6 has been shown to be part of the microtubule network and acts as a specific alpha-tubulin deacetylase, and has been suggested to be a potential therapeutic target in neurodegenerative disease (3).
• Synonyms: CMT2A; CMT2A2; CMT2A2A; CMT2A2B; CPRP1; HMSN6A; HSG; MARF

Reference Data

• Protein Families: Druggable Genome, Transcription Factors