PRAK (MAPKAPK5) Rabbit Polyclonal Antibody

SKU TA348439

Rabbit Polyclonal Anti-Phospho-MAPKAPK5(Thr182) Antibody

Product Data

• Application: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivity: Human, Mouse
• Modification: Phospho-specific
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Phospho-MAPKAPK5(Thr182) Antibody: A synthesized peptide derived from human MAPKAPK5 around the phosphorylation site of Threonine 182
• Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 60 kDa
• Gene Name: mitogen-activated protein kinase-activated protein kinase 5
• Database Link:
  NP_003659
  Q8IW41
• Background: The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.
• Synonyms: MAPKAP-K5; MK-5; MK5; PRAK
• Note: Phospho-MAPKAPK5(Thr182) Antibody detects endogenous levels of MAPKAPK5 only when phosphorylated at Threonine 182

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: MAPK signaling pathway