alpha smooth muscle Actin (ACTA2) Rabbit Polyclonal Antibody

CAT#: TA347823

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Rabbit Polyclonal Anti-alpha-SMA antibody

USD 380.00

4 Weeks

    • 100 ug

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Product Data
Applications WB
Recommended Dilution WB: 1:500-1:1000
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen The immunogen for anti-alpha-SMA antibody: Synthetic peptide corresponding to N terminal residues of Human alpha smooth muscle Actin.
Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration lot specific
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 45 KD
Gene Name actin, alpha 2, smooth muscle, aorta
Background Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. AATs are characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.
Synonyms AAT6; ACTSA; MYMY5
Note alpha-SMA antibody detects endogenous levels of alpha-SMA.
Reference Data
Protein Pathways Vascular smooth muscle contraction
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