H1oo (H1FOO) Rabbit Polyclonal Antibody

SKU TA347815

Rabbit Polyclonal Anti-Histone H1 Antibody

Product Data

• Application: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Histone H1 Antibody: A synthesized peptide derived from human Histone H1
• Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 21 kDa
• Gene Name: H1 histone family member O, oocyte specific
• Database Link:
  NP_722575
  Q8IZA3
• Background: H1FOO May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.
• Synonyms: H1.8; H1oo; osH1
• Note: Histone H1 Antibody detects endogenous levels of Histone H1

Reference Data