AZI2 Rabbit Polyclonal Antibody
Product Data | |
Application | WB |
---|---|
Recommended Dilution | WB: 1:500-1:2000 |
Reactivity | Human, Mouse, Rat |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | The immunogen for anti-AZI2 Antibody: A synthesized peptide derived from human AZI2 |
Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt |
Concentration | lot specific |
Purification | Immunogen affinity purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 48 kDa |
Gene Name | 5-azacytidine induced 2 |
Database Link | |
Background | AZI2 Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFN-beta promoter activation via TICAM1. Interacts with IKBKE, TBK1 and TICAM1. 2 isoforms of the human protein are produced by alternative splicing. |
Synonyms | AZ2; NAP1; TILP |
Note | AZI2 Antibody detects endogenous levels of AZI2 |
Reference Data | |
Protein Pathways | RIG-I-like receptor signaling pathway |
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