smooth muscle Myosin heavy chain 11 (MYH11) Rabbit Polyclonal Antibody
Product Data | |
Application | ELISA, WB |
---|---|
Recommended Dilution | ChIP/ChIP-seq (5ul/ChIP); ELISA (1:200); Western blotting (1:1,000) |
Reactivity | Human |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | The immunogen for anti-MYH11 antibody: human MYH11 (Myosin, Heavy Chain 11) using two KLH-conjugated synthetic peptides containing sequences from the C-terminal region of the protein. |
Concentration | lot specific |
Purification | Whole antiserum from rabbit containing 0.05% azide. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Gene Name | myosin, heavy chain 11, smooth muscle |
Database Link | |
Background | MYH11 (UniProtKB/Swiss-Prot entry P35749) is a smooth muscle myosin belonging to the myosin heavy chain family which function as major contractile proteins. MYH11 is involved in a pericentric inversion of chromosome 16 (inv(16)(p13q22)) which produces a chimeric transcript consisting of the N terminus of CBFb andthe C-terminal portion MYH11. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. |
Synonyms | AAT4; FAA4; SMHC; SMMHC |
Reference Data | |
Protein Pathways | Tight junction, Vascular smooth muscle contraction, Viral myocarditis |
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