AGO1 Rabbit Polyclonal Antibody

SKU TA347077

Rabbit Polyclonal EF2C1/2 Antibody

Product Data

• Application: ELISA, WB
• Recommended Dilution: ELISA (1:100); Western blotting (1:1,000)
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-EF2C1/2 antibody: human IEF2C1/2 (eukaryotic translation initiation factor 2C1 and 2), using a KLH-conjugated synthetic peptide containing a sequence from the C-terminal part of both EIF2C1 and EIF2C2.
• Concentration: lot specific
• Purification: Whole antiserum from rabbit containing 0.05% azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: argonaute 1, RISC catalytic component
• Database Link:
  NP_036331
  Q9UL18
• Background: IEF2C1 and 2 (UniProtKB/Swiss-Prot entries Q9UL18 and Q9UKV8) are members of the Argonaute family. These proteins are involved in short-interfering-RNA-mediated gene silencing. This process is mediated by the RISC (RNA induced silencing complex), a multicomponent nuclease that is able to degrade double stranded RNAs. The mRNA degradation is triggered by the association of specific siRNAs with their homologous mRNAs. IEF2C2 has been shown to be essential for embryonic development.
• Synonyms: EIF2C; EIF2C1; GERP95; Q99

Reference Data

• Protein Families: Druggable Genome