Aurora A (AURKA) Mouse Monoclonal Antibody [Clone ID: 2E3-C10-C11-G6]

SKU TA346888

Mouse Monoclonal Aurora Kinase A Antibody

Product Data

• Clone Name: 2E3-C10-C11-G6
• Application: IF, WB
• Recommended Dilution: WB: 1:500, IF: 1:50
• Reactivity: Human, Monkey
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: The immunogen for AURKA antibody: purified recombinant human Aurora Kinase A protein fragments expressed in E.coli.
• Buffer: ascites
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 46 kDa
• Gene Name: aurora kinase A
• Database Link:
  NP_940839
  O14965
• Background: The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
• Synonyms: AIK; ARK1; AURA; BTAK; PPP1R47; STK6; STK7; STK15

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Stem cell - Pluripotency
• Protein Pathways: Oocyte meiosis