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ABCG5 Mouse Monoclonal Antibody [Clone ID: 1B5E10]

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SKU
TA336947
Mouse Monoclonal ABCG5 Antibody (1B5E10)
Size:
100 ul
Conjugation:
Unconjugated
  $600.00
5 Days*
Bulk/Customize

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Specifications
Specifications
Product Data
Clone Name 1B5E10
Application ELISA, FC, IF, IHC, WB
Recommended Dilution Flow Cytometry: 1:200 - 1:400, ELISA: 1:10000, Immunohistochemistry: 1:200 - 1:2000, Western Blot: 1:500 - 1:2000, Immunohistochemistry-Paraffin: 1:200 - 1:2000, ICC/IF (Negative)
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Partial recombinant human ABCG5 (between residues 300-500) expressed in E. coli UniProt Q9H222.
Buffer PBS, 0.03% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration lot specific
Purification Ammonium sulfate precipitation
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name ATP binding cassette subfamily G member 5
Database Link
Background ABCG5 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCG5 is a member of the White subfamily. It functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. ABCG5 is expressed in a tissue-specific manner in the liver, colon, and intestine. Mutations in this protein may contribute to sterol accumulation and atheroschlerosis, and they have been observed in patients with sitosterolemia (1).
Synonyms STSL
Reference Data
Protein Categories Cardiovascular diseases, Membrane Proteins
Protein Families Druggable Genome, Transmembrane
Protein Pathways ABC transporters
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.