MCP1 (CCL2) Mouse Monoclonal Antibody [Clone ID: 2D8]

SKU
TA336914
Mouse Monoclonal CCL2/MCP1 Antibody (2D8)
  $680.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Clone Name 2D8
Application ELISA, FC, ICC/IF, IHC, WB
Recommended Dilution Western Blot: 1 - 3 ug/ml, Flow Cytometry: 1:200-1:400, Immunohistochemistry-Paraffin: 1:200-1:1000, ELISA: 1:10000, Immunohistochemistry: 1:200-1:1000, Immunocytochemistry/ Immunofluorescence: 1:200-1:1000
Reactivity Human, Mouse, Primate
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Purified recombinant fragment of human MCP1 expressed in E. coli. UniProt# P13500
Buffer PBS, 0.03% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration lot specific
Purification Ammonium sulfate precipitation
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 11 kDa
Gene Name C-C motif chemokine ligand 2
Database Link
Background This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
Synonyms GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF
Note This MCP1 (2D8) antibody is useful for Western blot, Immunohistochemistry on paraffin-embedded sections, Immunocytochemistry/Immunofluorescence, Flow Cytometry and ELISA.
Reference Data
Protein Categories Chemokines, Cytokines, Growth Factors, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction, NOD-like receptor signaling pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.