Fibronectin (FN1) Mouse Monoclonal Antibody [Clone ID: 2F4]
Product Data | |
Clone Name | 2F4 |
---|---|
Application | ELISA, FC, ICC/IF, IHC, WB |
Recommended Dilution | Flow Cytometry: 1:200 - 1:400, Immunohistochemistry: 1:200 - 11:1000, Immunohistochemistry-Paraffin: 1:200 - 1:1000, Western Blot: 1:500 - 1:1000, ELISA: 1:10000, Immunocytochemistry/ Immunofluorescence: 1:100 |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of human Fibronectin expressed in E. coli. [UniProt# P02751] |
Buffer | Preservative: 0.05% Sodium Azide. Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
Concentration | lot specific |
Purification | Ascites |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 262.6 kDa |
Gene Name | fibronectin 1 |
Database Link | |
Background | This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined. |
Synonyms | CIG; ED-B; FINC; FN; FNZ; GFND; GFND2; LETS; MSF |
Note | This Fibronectin (2F4) antibody is useful for Western blot, Immunohistochemistry on paraffin-embedded sections, Flow Cytometry and ELISA. |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein |
Protein Pathways | ECM-receptor interaction, Focal adhesion, Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer |
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