NRAMP1 (SLC11A1) Rabbit Polyclonal Antibody

SKU TA334162

Rabbit Polyclonal Anti-SLC11A1 Antibody

Product Data

• Application: WB
• Recommended Dilution: WB
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for Anti-SLC11A1 Antibody: synthetic peptide directed towards the C terminal of human SLC11A1. Synthetic peptide located within the following region: VLLTRSCAILPTVLVAVFRDLRDLSGLNDLLNVLQSLLLPFAVLPILTFT
• Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 61 kDa
• Gene Name: solute carrier family 11 member 1
• Database Link:
  NP_000569
  P49279
• Background: SLC11A1 is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and is a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in its gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease.
• Synonyms: LSH; NRAMP; NRAMP1
• Note: Immunogen sequence homology: Pig: 100%; Rat: 100%; Human: 100%; Bovine: 100%; Rabbit: 100%; Guinea pig: 100%; Dog: 93%; Goat: 93%; Horse: 93%; Mouse: 93%; Sheep: 93%

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Lysosome