STAT3 Mouse Monoclonal Antibody [Clone ID: 13A3-1]
Product Data | |
Clone Name | 13A3-1 |
---|---|
Application | WB |
Recommended Dilution | WB |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1, kappa |
Clonality | Monoclonal |
Immunogen | KLH conjugated modified synthetic peptide |
Buffer | This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. Previous lots of this product may have been formulated with 0.1% or 0.05% NaN3 instead of 0.09% NaN3. |
Concentration | lot specific |
Purification | The antibody was purified by affinity chromatography. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 88 kD |
Gene Name | signal transducer and activator of transcription 3 |
Database Link | |
Background | Tyrosine phosphorylation of STAT3 at Y705 occurs in response to LIF, IL-6, leptin, OSM, EGF, PDGF, and HGF. It plays a key role in cell growth and apoptosis through mediating expression of a variety of genes in response to the stimuli. |
Synonyms | ADMIO; APRF; HIES |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Acute myeloid leukemia, Adipocytokine signaling pathway, Chemokine signaling pathway, Jak-STAT signaling pathway, Pancreatic cancer, Pathways in cancer |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.