Oct-2 (POU2F2) Mouse Monoclonal Antibody [Clone ID: MRQ-2]
Product Data | |
Clone Name | MRQ-2 |
---|---|
Application | IHC |
Recommended Dilution | IHC: 1:25 - 1:100 |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1, kappa |
Clonality | Monoclonal |
Buffer | This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Gene Name | POU class 2 homeobox 2 |
Database Link | |
Synonyms | Oct-2; OCT2; OTF2 |
Note | Oct-2 is a transcription factor of the POU homeo-domain family that regulates B-cell-specific genes. It has been shown that this factor participates in transcriptional regulation during T-cell activation. The following show high levels of Oct-2 expression: Germinal center B-cells, mantle B-cells, monocytoid B-cells, and plasma cells. Various lymphomas are also positive for this marker including the following: B-chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, plasmacytoma, Burkitt lymphoma, diffuse large B-cell lymphoma, T-cell rich B-cell lymphoma, and nodular lymphocyte predominant Hodgkin lymphoma. |
Reference Data | |
Protein Families | Transcription Factors |
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