PMS1 Rabbit Polyclonal Antibody

SKU TA327321

PMS1 Rabbit Polyclonal Antibody

Product Data

• Application: ELISA, WB
• Recommended Dilution: WB,1:500 - 1:2000; ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Buffer: Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 106kDa
• Gene Name: PMS1 homolog 1, mismatch repair system component
• Database Link:
  NP_000525
  P54277
• Background: This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.
• Synonyms: HNPCC3; hPMS1; MLH2; PMSL1

Reference Data

• Protein Families: Druggable Genome, Transcription Factors