ARF6 Rabbit Polyclonal Antibody

SKU TA326709

Rabbit Polyclonal ARF6 Antibody

Product Data

• Application: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: ARF6 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human ARF6.
• Buffer: ARF6 antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: ARF6 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: Predicted: 19 kDa; Observed: 18 kDa
• Gene Name: ADP ribosylation factor 6
• Database Link:
  NP_001654
  P62330
• Background: The ADP-ribosylation factor 6 (ARF6) is a member of the ARF family, which is part of the RAS superfamily (1). The ARF proteins are small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D (2). The product of this gene is localized to the plasma membrane (3), and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling (4).
• Synonyms: DKFZp564M0264

Reference Data

• Protein Pathways: Endocytosis, Fc gamma R-mediated phagocytosis