LC3C (MAP1LC3C) Rabbit Polyclonal Antibody

SKU TA326684

Rabbit Polyclonal MAP1LC3C Antibody

Product Data

• Application: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: MAP1LC3C antibody was raised against an 18 amino acid peptide near the carboxy terminus of human MAP1LC3C.
• Buffer: MAP1LC3C antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: MAP1LC3C antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: Predicted: 16 kDa; Observed: 16 kDa
• Gene Name: microtubule associated protein 1 light chain 3 gamma
• Database Link:
  NP_001004343
  Q9BXW4
• Background: Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and plasticity (1). MAP1LC3C belongs to the MAP1 LC3 family of proteins that form mature complexes with MAP1A and MAP1B which are thought to be important in the formation and development of axons and dendrites (2). MAP1LC3C is one of three isoforms of MAP1LC3, the mammalian homolog of yeast ATG8, an essential autophagy protein. These isoforms exhibit distinct expression patterns and MAP1LC3C, like MAP1LC3A but not MAP1LC3B, is post-translationally modified, suggesting the three isoforms may have different physiological functions (3).
• Synonyms: ATG8J; LC3C

Reference Data