Piccolo (PCLO) Rabbit Polyclonal Antibody

SKU TA326449

Rabbit Polyclonal Anti-Piccolo Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 1:1000
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Full length protein
• Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: piccolo presynaptic cytomatrix protein
• Database Link:
  NP_055325
  Q9Y6V0
• Background: Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains . In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones) . Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1 .
• Synonyms: ACZ
• Note: Detects ~550kDa corresponding to the molecular weight of Picollo. Multiple isoforms can be detected. No cross-reactivity to Bassoon.

Reference Data