Actin Regulatory Protein CAPG (CAPG) Rabbit Polyclonal Antibody
Product Data | |
Application | IHC, WB |
---|---|
Recommended Dilution | WB: 1000-5000 WB positive control: Jurkat and RAW264.7 cells IHC: 50-200 Positive control: Human brain Predicted cell location: Cytoplasm or Nucleus |
Reactivity | Human, Mouse, Rat |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein corresponding to C terminal 250 amino acids of human capping protein (actin filament), gelsolin-like |
Buffer | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 38 kDa |
Gene Name | capping actin protein, gelsolin like |
Database Link | |
Background | This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene. |
Synonyms | AFCP; HEL-S-66; MCP |
Reference Data |
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