Kallikrein 7 (KLK7) Rabbit Polyclonal Antibody

SKU
TA324188
Anti-KLK7 Rabbit Polyclonal Antibody
$305.00
2 Weeks*
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB: 500-2000
WB positive control: Mouse brain and kidney tissue
IHC: 25-100
Positive control: Human esophagus cancer
Predicted cell location: Cytoplasm, Nucleus
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from 30-253 amino acids of human kallikrein-related peptidase 7kallikrein-related peptidase 7
Buffer PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 28 kDa
Gene Name kallikrein related peptidase 7
Database Link
Background This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation; the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis; and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene; which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.
Synonyms hK7; PRSS6; SCCE
Reference Data
Protein Families Druggable Genome, Secreted Protein
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.