Caspase 2 (CASP2) Rabbit Polyclonal Antibody

SKU TA324171

Anti-CASP2 Rabbit Polyclonal Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 1000-2000; WB positive control: Human fetal kidney and lung tissue; IHC: 100-300; Positive control: Human urinary bladder; Predicted cell location: Cytoplasm
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to N terminal 201 amino acids of Human Caspase-2
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 51 kDa
• Gene Name: caspase 2
• Database Link:
  NP_001215
  P42575
• Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways; cell cycle maintenance; and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease; Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Synonyms: CASP-2; ICH1; NEDD-2; NEDD2; PPP1R57

Reference Data

• Protein Families: Druggable Genome, Protease