Fibrillin 1 (FBN1) Rabbit Polyclonal Antibody

SKU TA323728

Anti-FBN1 Rabbit Polyclonal Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 50-200; Positive control: Human thyroid cancer; Predicted cell location: Cytoplasm
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 2837-2853 amino acids of Human fibrillin 1
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: fibrillin 1
• Database Link:
  NP_000129
  P35555
• Background: This gene encodes a member of the fibrillin family. The encoded protein is a large; extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome; isolated ectopia lentis; autosomal dominant Weill-Marchesani syndrome; MASS syndrome; and Shprintzen-Goldberg craniosynostosis syndrome.
• Synonyms: ACMICD; ECTOL1; FBN; GPHYSD2; MASS; MFS1; OCTD; SGS; SSKS; WMS; WMS2

Reference Data

• Protein Families: Druggable Genome