Heparanase 1 (HPSE) Rabbit Polyclonal Antibody

SKU TA323271

Anti-HPSE Rabbit Polyclonal Antibody

Product Data

• Application: WB
• Recommended Dilution: ELISA: 1:2000-5000, WB: 1:500-2000
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a C terminal 250 amino acids of human heparanase
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 61 kDa
• Gene Name: heparanase
• Database Link:
  NP_001092010
  Q9Y251
• Background: Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix. The protein encoded by this gene is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. In addition; this cleavage can release bioactive molecules from the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.
• Synonyms: HPA; HPA1; HPR1; HPSE1; HSE1

Reference Data

• Protein Families: Secreted Protein
• Protein Pathways: Glycosaminoglycan degradation, Metabolic pathways