Cytochrome C Oxidase subunit VIb (COX6B1) Rabbit Polyclonal Antibody

CAT#: TA323103

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Anti-COX6B1 Rabbit Polyclonal Antibody



USD 380.00


Availability*
In Stock

Size
    • 100 ul


Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 500-2000
WB positive control: LOVO and HepG2 cell lysates
IHC: 50-200
Positive control: Human prostate cancer
Predicted cell location: Cytoplasm
Reactivities Human, Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Full length fusion protein
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name cytochrome c oxidase subunit 6B1
Background Cytochrome c oxidase (COX); the terminal enzyme of the mitochondrial respiratory chain; catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer; and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1; COX6BP-2 and COX6BP-3 have been found on chromosomes 7; 17 and 22q13.1-13.2; respectively.
Synonyms COX6B; COXG; COXVIb1
Reference Data
Protein Pathways Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease
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