FOXO1 Rabbit Polyclonal Antibody
Product Data | |
Application | IF, IHC, WB |
---|---|
Recommended Dilution | WB: 500-2000 WB positive control: Hela cell lysate IHC: 25-100 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm and Nucleus |
Reactivity | Human, Mouse, Rat |
Modification | Phospho-specific |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Peptide sequence around phosphorylation site of serine 256 (A-A-S(p)-M-D) derived from Human FKHR. |
Buffer | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 70 kDa |
Gene Name | forkhead box O1 |
Database Link | |
Background | This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. |
Synonyms | FKH1; FKHR; FOXO1A |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Insulin signaling pathway, Pathways in cancer, Prostate cancer |
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