NME6 Rabbit Polyclonal Antibody
Product Data | |
Application | WB |
---|---|
Recommended Dilution | WB: 200-1000 WB positive control: Mouse spleen and intestinum crassum tissue |
Reactivity | Human, Mouse, Rat |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Full length fusion protein |
Buffer | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 21 kDa |
Gene Name | NME/NM23 nucleoside diphosphate kinase 6 |
Database Link | |
Background | Nucleoside diphosphate (NDP) kinases (EC 2.7.4.6); such as NME6; are ubiquitous enzymes that catalyze transfer of gamma-phosphates; via a phosphohistidine intermediate; between nucleoside and dioxynucleoside tri- and diphosphates. Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism; using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis. |
Synonyms | IPIA-ALPHA; NDK 6; NM23-H6 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Metabolic pathways, Purine metabolism, Pyrimidine metabolism |
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