CRMP3 (DPYSL4) Rabbit Polyclonal Antibody

CAT#: TA322499

Anti-DPYSL4 Rabbit Polyclonal Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 30 μg Lane: Human fetal brain tissue Primary antibody: TA322499 (DPYSL4 Antibody) at dilution 1/500 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 20 seconds

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA322499 (DPYSL4 Antibody) at dilution 1/15 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA322499 (DPYSL4 Antibody) at dilution 1/15, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA322499 (DPYSL4 Antibody) at dilution 1/15 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA322499 (DPYSL4 Antibody) at dilution 1/15, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-1000
  WB positive control: Human fetal brain tissue
  IHC: 25-100
  Positive control: Human cervical cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 507-522 amino acids of Human dihydropyrimidinase-like 4
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 62 kDa
• Gene Name: dihydropyrimidinase like 4
• Database Link:
  NP_006417
  Entrez Gene 25417 RatEntrez Gene 26757 MouseEntrez Gene 10570 Human
  UniProt ID O14531
• Background: Collapsin response mediator protein 3 is an enzyme that in humans is encoded by the CRMP3 gene.It is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton.And plays a role in axon guidance; neuronal growth cone collapse and cell migration.Homotetramer; and heterotetramer with CRMP1; DPYSL2; DPYSL3 or DPYSL5. Interacts with PLEXA1. Phosphorylated upon DNA damage; probably by ATM or ATR.
• Synonyms: CRMP3; DRP-4; ULIP4